The key with MioXM is that it is a very fast wired hardware MIDI router.
It seems to have no problem feeding clock signals to many devices simultaneously.
With this kind of router (which is in some ways more akin to a network “switch” than a “router” because its transport logic is built into the firmware), you’re avoiding daisy-chaining through your gear’s MIDI ports. You’re wiring everything directly into the MioXM and it acts a super-fast hub.
I’ve configured my MioXM to filter certain messages to specific ports, and limited the routing so only what I need to send is sent. This way each device is seeing only what it needs to see. This kind of optimization is pretty much impossible when you use device-chaining.
I’m about to add a BomeBox to this network to provide even finer hardware-based mapping and control over MIDI. I’ll be happy to report on what it does, but the idea is to enable my KMI Softstep pedal to control my BeatBuddy more effectively. I’ll be able to use short-press, long-press and multiple-tap toggle on the Softstep keys to command BeatBuddy start, stop, fill and next part, along with similar control over my other midi devices.